# Browse by Subject "Biophysics, Medical"

• (1994)
In biological systems, DNA/RNA-protein interactions as well as drug-DNA interactions play important roles in genetic processes. A fundamental understanding of these processes requires a detailed structural knowledge of ...

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• (1984)
The concentrations of mobile high energy phosphorus metabolites and intracellular pH of Langendorff-perfused rabbit heart have been determined under control and reduced flow conditions. Absolute concentration determination ...

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• (1995)
Magnetic resonance (MR) is a rapidly growing versatile and non-destructive tool for investigation of various aspects of biochemistry, physiology and disease. It is valuable to evaluate the new MR techniques and apply them ...

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• (2009)
C-type lectins are a prominent class of pathogen recognition receptors in the innate immune system. The three pathogen recognition lectins studied in this thesis are the mannose binding protein (MBP), the dendritic ...

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• (1991)
We have obtained high-field (11.7 T), high-resolution $\sp{13}$C solid state "magic angle" sample spinning nuclear magnetic resonance (MAS NMR) spectra of a variety of model phospholipids, sphingolipids, myelin and white ...

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• (1993)
Guinea pig left atria were suspended in a tissue bath of normal Krebs-Henseleit solution which was aerated with 95% O$\sb2$/5% CO$\sb2$ and maintained at 27$\sp\circ$C. The atria were attached to a force transducer and ...

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• (2004)
Near infrared spectroscopy (NIBS) has been used for determination of tissue optical properties. This technique has been especially useful for in vivo monitoring of hemodynamics and oxygen saturation in tissue. For this ...

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• (2006)
The differences that cause the conformational heterogeneity of CYP3A4 in other solubilization systems have complicated the complete biophysical characterization in comparison to similar soluble bacterial counterparts. The ...

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• (2009)
Mechanical proteins perform a vital role in cells by transmitting and bearing mechanical forces involved in cell growth, locomotion, and adhesion. Little is known at the molecular level that explains how such proteins are ...

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• (1994)
Magnetic Resonance Imaging (MRI) holds enormous potential for exploring the functional centers of a living brain in vivo. Among the MRI techniques a number of different approaches have provided initial success. The focus ...

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• (1988)
The site of ultrasonic absorption in suspensions of negatively-charged large unilamellar vesicles (LUVs) was investigated. The ultrasonic absorption per wavelength, $\alpha\lambda$, was determined for suspensions of LUVs ...

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• (1989)
The pH of the tumor microenvironment may be important in assessment of response to hyperthermic therapy. Little clinical in vivo data is available during such therapy due to the inherent limitations of the microelectrode ...

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• (1993)
In this thesis, the electron paramagnetic resonance (EPR) methods for simultaneous measurement of intra- and extracellular concentration of oxygen ( (O$\sb2$)) in viable cells have been developed.

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• (1979)

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• (1988)
A fundamental investigation of the potential of nitroxides and O$\sb2$ for enhancement of magnetic resonance imaging (MRI) contrast in vivo is presented. The effect of these species on proton relaxation in both aqueous ...

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• (1992)
The effects of heat and of ultrasound were investigated in the terminally- differentiated erythrocyte using hemolysis as end-point. The heat-induced hemolysis of chicken and rat red blood cells (RBC's) was determined between ...

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• (2003)
By attaching the fluorophore directly onto the ligand-binding domain, we have created out of the ER a molecular sensor through which we can probe directly the conformational state of the receptor with high sensitivity. ...

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• (2006)
For decades there has only been anecdotal data regarding how difficult it is to crystallize membrane proteins but these facts are never rigorously evaluated, because virtually no one can report all the reasons why membrane ...

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• (1996)
Chemotherapy with anticancer drugs is one of the main method of cancer treatment. The exploitation of the stereochemical interactions between anticancer drugs and DNA is of great importance for the ultimate clinical advances ...

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• (1993)
The multinuclear magnetic relaxation behavior of heart muscle from chicken, pork, and beef is investigated. Nonlinear regression analysis of the $\sp1$H transverse magnetization decay yields the best fit with three exponential ...

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