Browse by Subject "translocation"
Now showing items 1-5 of 5
Characterization of leucyl-TRNA synthetase from homo sapiens and escherichia coli in aminoacylation, amino acid editing and interdomain interactions (2010-05-14)Aminoacyl-tRNA synthetases (aaRSs) are ancient enzymes that charge tRNA with its cognate amino acid. In order to maintain fidelity during protein synthesis, editing mechanisms ensure that tRNAs are accurately charged. ...
Construction of CNFY-CNF1 Chimera Protein for Study of Differential pH Dependent Activity of CNF Proteins (2014-05-30)In this thesis we will explore the topic of cytotoxic necrotizing factors (CNFs) and show the creation of chimeric constructs to further test the details of CNF translocation into the cell. The CNF family of toxins is under ...
(2012-02-01)The aim of this thesis is to further define the entry and trafficking pathways of the dermonecrotic toxin family composed of related AB toxins whose members induce dermonecrosis upon injection into animal skin. The ...
(Illinois Natural History Survey, 2015-01-20)
(2006)Bloom helicase (BLM) is a member of the RecQ helicase family, a group of 3’ to 5’ helicases which are homologs of the RecQ protein found in E. coli. Besides the canonical helicase function of unwinding duplex DNA, the RecQ ...