Browse by Subject "P450"
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Engineering of an efficient and enantioselective biocatalyst for the preparation of chiral pharmaceutical intermediates (2011-08-26)This Ph.D. thesis focuses on the engineering of an efficient and enantioselective biocatalyst via direct evolution and genetic engineering for the enantioselective hydroxylation of non-activated carbon atom, a useful but ...
(2015-02-25)CYP19A1 or aromatase, is a human steroidogenic P450 important for estrogen biosynthesis in humans. Over activation of aromatase results in malignancies of the breast tissue, especially in post menopausal women. In fact, ...