Browse by Subject "cystic fibrosis"
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(2010-05-14)While cystic fibrosis (CF) is commonly thought of as a lung disease, since it’s first description 70 years ago we have come to understand that loss of CFTR (cystic fibrosis transmembrane conductance regulator) function ...
Less toxic yet still resistance evasive amphotericins and atomistic probing of the amphotericin B ion channel (2015-01-22)Amphotericin B (AmB) is a polyene macrolide natural product with two major functions: antifungal activity and ion channel formation. For over 50 years AmB has remained the last line of defense against systemic fungal ...
(2013-05-24)Cystic fibrosis (CF) patients battle life-long pulmonary infections with the respiratory pathogen Pseudomonas aeruginosa (PA). A favorable niche for PA growth is provided by an overabundance of mucus in CF airways. When ...