Files in this item
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application/pdf ![]() | Poster | |
application/pdf ![]() | Image |
Description
Title: | Unraveling cell nucleus structure |
Author(s): | Liu, Wenjie |
Subject(s): | Bioengineering |
Abstract: | Cell nucleus stores our genetic information within DNA. It is estimated that about 3.2 billion bases of DNA (around 1 m in length) reside in the nucleus, which is packaged as chromatins. The local structure of chromatin lies the blueprint that dictates everything a cell does. Such small and fascinating structure was not able to be fully resolved under microscope several years ago. With recent advance in super-resolution imaging, this becomes possible. My research looks at those tiny structures at single cell level beyond the diffraction limit. I investigated the dynamic of nucleus structure on cell function with environmental pollution. We discovered that Perfluorooctanoic acid (coating material for non-stick pot) could change the heterochromatin structure, resulting in cancerous cell fate. |
Issue Date: | 2019 |
Type: | Text image |
URI: | http://hdl.handle.net/2142/103707 |
Rights Information: | Copyright 2019 Wenjie Liu |
Date Available in IDEALS: | 2019-05-03 |