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Title:Preventing bacterial infection of implants for bone regeneration
Author(s):Dewey, Marley
Contributor(s):Collins, Alan; Harley, Brendan
Subject(s):Bacterial Infection
Abstract:Bacterial infection during surgical operations is a challenge for many tissue engineering approaches for wound healing. One of the design principles of implants to replace missing, damaged, or diseased tissue is preventing the aggregation of bacteria on these. Bacteria present within a wound site can prevent healing and lead to further complications such as abscess formation and additional surgeries to remove the infected tissue. Additionally, some bacterial strains have demonstrated resistance to antibiotics, the typical method to eliminate bacteria. Here, pseudomonas aeruginosa bacteria (orange) adhere to a collagen-based biomaterial (blue) for regeneration of large missing segments of bone. Researchers are currently investigating methods to prevent bacterial adhesion on these biomaterials through the addition of natural manuka honey, which has been shown to disrupt even antibiotic-resistant bacteria.
Issue Date:2021
Description:The Harley Lab, the Whitaker Lab, the Institute for Genomic Biology, the Beckman Institute
Rights Information:Copyright 2021 Marley Dewey
Date Available in IDEALS:2021-04-12

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