(2009)Daily rhythms in behavior, physiology, and metabolism are synchronized to the solar cycle by the suprachiasmatic nucleus (SCN) of the mammalian brain. Cells of the SCN undergo a near 24-hour pattern of cellular events that ...
Sampling Strategies for Characterization of Neuropeptides Using Mass Spectrometry and Functional Implications Into Cell -Cell Signaling (2009)The peptides with roles in the development of the pituitary were analyzed using transgenic mice. Hes1 KO is a genetically modified mouse that lives only e18.5 (embryonic days). Anterior pituitaries of Hes1 null mice exhibit ...
(2006)In the next experiments, the ultrastructure of the visual cortex was examined in young Fmr1 knockout and wildtype mice. The rate of developmental synaptogenesis between the two genotypes was similar, but Fmr1 knockout ...
Investigation of the Signaling Mechanisms of the Pineal Hormone Melatonin in the in Vitro Rat Suprachiasmatic Nucleus (2001)Virtually all eukaryotic organisms on Earth experience daily oscillations in behavior, physiology, and metabolism. These circadian (Latin: circa = about, dies = day) rhythms are controlled in mammals by the master biological ...
Developmental Cell Death and Androgens Affect Neuron Number in the Primary Visual Cortex of Male and Female Rats (2000)Finally, I investigated the effect of neonatal hormone manipulations (females + estradiol, females + DHT) upon cell death in the developing rat posterior cortex. DHT implantation in females decreased the proportion of cells ...