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Browse Dissertations - Neuroscience by Title
Now showing items 18-37 of 145
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(2006)Voltage-gated calcium channels contain a pore-forming alpha1 subunit and auxiliary alpha2delta, beta and gamma subunits. Of the three auxiliary subunits, gamma is least understood. Cardiac myocytes express three gamma ...
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(1994)The brain renin-angiotensin system (RAS) is a known regulator of cardiovascular function. The present studies investigated the cardiovascular effects of the pharmacological interruption of this system in hypertensive inbred ...
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(1997)Neuronal growth can be controlled in vitro by plating cells at low density and by differential adhesion between the cell and substrate. This principle was used to develop a technology to pattern neurons in reduced networks ...
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PDF (7MB)
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(2004)Several postmortem studies of schizophrenia reveal that despite normal numbers of cortical neurons, patients exhibit anatomical reductions in synaptic connectivity. Prefrontal regions have been implicated as a site of ...
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(2007)cGKI and cGKII are paralogous serine/threonine protein kinases. In an effort to determine the mechanism by which the circadian molecular clockworks differentially regulates the activity of these kinases a comparative biology ...
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(1995)A cholinergic agonist, carbachol, has been shown to shift the phase of circadian rhythms in rodents when injected intracerebroventricularly. However, the site and receptor type mediating this action have been unknown. The ...
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(2008)In chapter 4, I investigated subcortical structures (i.e., thalamus and IC) involved in the processing of communication signals, using egr1 (an immediate early gene) as a molecular marker for brain activation. Three ...
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(1999)Chromaffin-adrenocortical cellular interactions have become recognized as an important component of adrenocortical regulation, however, the mechanisms by which chromaffin cells modulate adrenocortical function are not well ...
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(2008)To investigate possible neurochemical mechanisms, densities of D1 and D2 dopamine receptors and dopamine transporter (DAT) were measured in the prefrontal cortex of genistein-treated rats by Western blot. D1 and D2 densities ...
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(2001)Animals actively influence the content and quality of sensory information they acquire through the positioning of peripheral sensory surfaces. Investigation of how the body and brain work together for sensory acquisition ...
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Dendritic properties of inhibitory thalamic neurons: implications in sub-cortical sensory processing (2012-06-27)This dissertation is focused on understanding the cellular mechanisms underlying thalamocortical network activities. Specifically, I am interested in how inhibitory neurons of the thalamus process information received from ...
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(2000)The general goal of this thesis is to better understand the ways individual layers of the cat lateral geniculate nucleus (LGN) contribute to visuomotor behavior. This thesis has two main outcomes. First, the normal ...
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(2000)The goals of the studies described in this thesis were to elucidate the development of the hypoxic responses of rat caudal hypothalamic neurons and to determine the specific membrane properties responsible for these ...
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(2013-02-03)The goal of this project is to adapt diffusive optical imaging (DOI) to study the brains of songbirds. We study songbirds because they have a special ability to learn songs and to use them to communicate. We choose to use ...
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(2000)Finally, I investigated the effect of neonatal hormone manipulations (females + estradiol, females + DHT) upon cell death in the developing rat posterior cortex. DHT implantation in females decreased the proportion of cells ...
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(2001)In the nervous system, immediate-early gene (IEG) induction is observed following exposure to salient events. Although the function of IEGs is not fully understood, one prominent model suggests that they are needed to ...
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(2014-05-30)During infancy and childhood, almost every person will impacted by infection. Neonates, due to their immature immune system, are especially vulnerable to respiratory infection and are more prone to hospitalization. ...
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(2013-05-24)Previous work has shown that exposure to bisphenol A (BPA) during early development can affect behavior and sexual differentiation of the brain in rodents, although few studies have examined effects on cognitive behavior ...
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(2009)Polychlorinated biphenyls (PCBs) and methylmercury (MeHg) are ubiquitous environmental contaminants to which humans are exposed, primarily via consumption of contaminated fish and seafood. Developmental exposure to these ...
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(2015-04-22)Polychlorinated biphenyls (PCBs) are persistent organic pollutants that can accumulate in the adipose tissue. PCBs can then be mobilized and transported across the placenta and through breast milk to affect developing ...
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Now showing items 18-37 of 145