Endometriosis is a debilitating disease that is diagnosed in 0.5-5% fertile and 25-40% of infertile women, but the underlying mechanisms involved in progression of the disease as well as the associated infertility are yet ...

Reactive oxygen species have received an increasing amount of attention over the past decade, not only due to their role in oxidative damage, but also because of their participation as second messengers on the relay of ...

Taken together, our data suggested that basigin plays multiple roles during implantation by regulating uterine stromal cell differentiation, stimulating MMP production and inducing the expression of pro-inflammatory genes.

Uterine leiomyomas are known as the most commonly occurring neoplasms in women during their reproductive years. The overall incidence of these benign tumors can be as high as 70-80%, which represents a significant health ...

The study of the dysregulation of the transcriptome in diseases like cancer and drug abuse can offer insights into preventive and therapeutical remedies, as well as targets for future basic and applied research. The ...

Neuropsychiatric illnesses pose a large burden on society, including health care costs, the need for special education and counseling, and emotional hardship for both sufferers and care givers. For many, these burdens are ...

These studies were conducted for a greater understanding of the function of the Fused toes (Ft) locus, which includes six genes: homeobox genes: Irx3, Irx5 and Irx6 and three other genes: Fto, Fts, and Ftm, during male and ...

Endometriosis is a common gynecological disorder affecting 6%–10% of women of reproductive age and 35%–50% of women experiencing chronic pelvic pain and/or infertility. The most widely accepted mechanism of this disease ...

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of reproductive age women and has received substantial research time and financial support over the past few decades. Despite on-going research efforts, ...