Dept. of Chemistry
A synthesis enabled understanding of Amphotericin B leading to derivatives with improved therapeutic indices (2014-07-16)Systemic fungal infections represent a significant contributor to human morbidity and mortality. To lower the impact of invasive fungal pathogens on the global population, more progress must be made in the areas of ...
(2010-10-20)Many small molecules targeted for synthesis in the laboratory are inherently modular in their construction. Harnessing this modularity towards a unified strategy for the synthesis of these compounds, this dissertation ...
Colorimetric sensor array for identification of fungi & ultrasonic spray synthesis for supercapacitor materials (2015-11-18)In this thesis, functional materials synthesis and fabrication is described within the two areas of (1) colorimetric sensor array for identification of fungi, and (2) ultrasonic spray synthesis for supercapacitor electrode ...
Mechanisms of multielectron redox catalysis with low-valent cobalt: defining the roles of coordination number, stereoelectronics and field effects in selectivity for two-electron chemistry (2015-10-22)Employing first-row transition metals in catalytic two-electron transformations remains a synthetic challenge. In order to overcome the common and often deleterious single-electron reactivity, an electron rich ligand was ...
Mass spectrometry-based identification and quantitation of endogenous peptides in complex biological matrices (2015-10-14)In the brain, chemical signaling molecules transfer information from cell-to-cell to modulate mood, behavior, and physiological functions like metabolism and circadian rhythm. The research presented in this dissertation ...