School of Molecular and Cellular Biology
(2015-02-24)Lanthipeptides are a family of ribosomally synthesized and posttranslationally modified natural products defined by the characteristic thioether crosslinks lanthionine and methyllanthionine. Among the various biological ...
(2015-02-25)CYP19A1 or aromatase, is a human steroidogenic P450 important for estrogen biosynthesis in humans. Over activation of aromatase results in malignancies of the breast tissue, especially in post menopausal women. In fact, ...
(2015-01-13)Cellular heterogeneity between brain regions has been attributed to differences in neurons, although differences between astrocytic glia of distinct brain regions are emerging. Relatively little is understood concerning ...
(2015-02-05)RNA is one of the major macromolecules essential for all known forms of life. RNA in the cell is subject to many types of damage as DNA, and the ubiquitous RNA degradation by surveillance machinery is an important way to ...
(2015-01-08)Estrogens, acting via estrogen receptor α (ERα), stimulate the proliferation and metastatic potential of breast cancers, and likely some ovarian, endometrial, and cervical cancers. Endocrine therapy targeting these cancers ...