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Browse Dept. of Biochemistry by Contributor "Kelleher, Neil L."
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(2013-05-28)Information at the protein level is essential to understand the functioning of a biological system. The goal of proteomics is to provide such information as protein identities, post-translational modifications (PTMs) on ...
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(2008)We have also developed a top down-like approach (middle down) which analyzes large peptides to characterize PTM profiles on histone H3. Interestingly, we were able to conclude that methylation and acetylation levels on ...
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(2008)Interest in chromatin biology has increased dramatically in the past decade due to discoveries of its involvement in important cellular activities including epigenetics, development, gene activity, etc. Changes in chromatin ...
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(2012-02-01)Cellular senescence, an irreversible cell cycle arrest induced by a diversity of stimuli, has been considered as an innate tumor suppressing mechanism with implications and applications in cancer therapy. The senescence ...
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(2011-01-21)Nonribosomal peptides are an important class of natural products including the life-saving antibiotics penicillin and vancomycin and the deadly microcystins and cereulide. This important category of natural products is ...
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Now showing items 1-5 of 5