We are inviting IDEALS users, both people looking for materials in IDEALS and those who want to deposit their work, to give us feedback on improving this service through an interview. Participants will receive a $20 VISA gift card. Please sign up via webform. # Browse Division of Nutritional Sciences by Title • (1998) The biochemical mechanisms contributing to 'zinc deficiency-induced anorexia' are not understood, although the recent discovery of hypothalamic appetite-controlling neuropeptides suggests that this anorexia may ultimately ... application/pdf PDF (4MB) • (2008) The incidence of type 2 diabetes is rapidly expanding. Some of the more obvious pathologies associated with it include: defective glucose metabolism, obesity, cardiovascular disease and an inability to mount an effective ... application/pdf PDF (2MB) • (1997) In a final study, CHB was found to mediate a monofunctional DNA-directed increase in GST subunit Ya$\sb2,$Yc$\sb2$and QR mRNA levels, without a concomitant increase in mRNA levels of CYP 1A. This suggests that, in the ... application/pdf PDF (8MB) • (1997) Neonatal hypoglycemia is common in infants of diabetic mothers (IDM). The hypoglycemia is believed to result from persistent insulin hypersecretion due to the elevated glucose concentration in utero. The mechanism for the ... application/pdf PDF (8MB) • (1998) The second specific aim of this research was to investigate the regulation of insulin-like growth factor binding protein-1 production following exercise. Prolonged exercise increased plasma and hepatic levels of IGFBP-1. ... application/pdf PDF (8MB) • (2015-08-20) Vaginal microbes exert a strong influence on women's reproductive health. Perturbations in the vaginal microbiome have been associated with serious sequelae, such as bacterial vaginosis (BV) and pregnancy complications. ... application/pdf PDF (3MB) • (2008) This knockout mouse presents itself as an ideal model for the continued investigation of HUFA including AA, DHA and DPA. application/pdf PDF (11MB) • (2015-12-04) Childhood obesity is a nutrition-related disease with multiple underlying etiologies. The gut microbiota is thought to be a contributor in the development of obesity by fermentation of non-digestible polysaccharides to ... application/pdf PDF (6MB) • (2018-12-06) Colorectal cancer (CRC) is the third leading cause of cancer, and the second leading cause of cancer death in the United States (US). Recent evidence links consumption of a diet high in animal protein and fat as an ... application/pdf PDF (5MB) • (2012-06-27) Obesity is associated with a host of co-morbidities including hyperglycemia, insulin resistance, Type II diabetes (T2D), and cognitive deficit. The present study examined the modulation of weight, blood metabolites, ... application/pdf PDF (1MB) • (2007) Sulforaphane increases gene expression through binding of the Nrf2 transcription factor to the antioxidant response element (ARE) in the promoter region of target genes. Because SF and ER increased MRP1 expression at the ... application/pdf PDF (3MB) • (2004) Pancreatic beta-cells may balance glucose-stimulated insulin synthesis and secretion with the proteasome activity to regulate protein concentrations in the endoplasmic reticulum (ER). During this process, reactive oxygen ... application/pdf PDF (11MB) • (1998) Conclusions. Interferon-$\gamma,$but not IFN-$\alpha,$has a direct pathogenic role on the pancreatic$\beta$-cell. Early expression of IFN-$\alpha$by the$\beta$-cell may contribute to insulitis whereas IFN-$\gamma,\$ a ...

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• (2013-08-22)
For all stages of pancreatic cancer, the 5-year survival rate from the time of diagnosis is 6%, with the median survival rate being only 6 months. This poor prognosis for pancreatic cancer is due to its aggressive nature ...

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• (2018-09-05)
“‘You'll live longer and you'll be healthier too,’ he answered. ‘Because as we were saying today, there's nothing in the world like eating moderately to live a long life.’ ‘If that's the way things are,’ I thought to myself, ...

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• (2011-05-25)
Abstract This thesis covers a variety of topics and analyses related to early nutrition on the impact it has on the development of lung immunity in the piglet. In the first section, an introduction is given. In short, ...

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• (2015-04-22)
In 2013, 11.4% of births in the United States occurred preterm.1 Due to the immaturity of the gastrointestinal tract, these infants are at increased risk of feeding intolerance and necrotizing enterocolitis (NEC). NEC is ...

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• (2018-03-26)
Eating behavior in children is influenced by both genetic and environmental determinants. In the first two years of life, children develop food preferences and dietary habits as they transition from a milk-based diet to ...

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• (2010-08-31)
Hypoglycemia is associated with a variety of adverse behaviors including fatigue, confusion, social withdrawal, anhedonia and depressive-like behaviors. While these clinical symptoms are well characterized, the mechanisms ...

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• (2009)
Aged mice exhibit a heightened central inflammatory cytokine response, as well as prolonged hippocampal-dependent cognitive deficits, compared to adults when administered lipopolysaccharide (LPS) to mimic a peripheral ...

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