Center for Biophysics and Computational Biology
Browse Collections of Items
(2019-12-12)Over the last two decades, synthetic biology has emerged as a critical toolset for genetic engineering. Synthetic gene circuits have been engineered for a variety of uses from functional modules to increasing biosynthetic ...
Solid-state NMR structural investigations of alpha-synuclein fibrils derived from Lewy Body dementia brain tissue (2019-11-27)Amyloid fibrils composed of the neural protein α-synuclein (α-syn) are the primary proteinaceous constituent of insoluble deposits in the brain that are the defining pathological feature of neurodegenerative diseases, ...
(2019-11-21)Two-dimensional (2D) materials have transformed single molecule nanoscale manipulation and molecular detection. Graphene is one such 2D material whose single-atom thickness and high in-plane electrical conductivity enables ...
Super-resolution imaging of glutamate receptors in cultured hippocampal neurons under basal and LTP conditions (2019-07-01)The locations and dynamics of glutamate synaptic receptors—the AMPA receptors (AMPARs) and NMDA receptors (NMDARs)—located on the postsynaptic membrane of nerve cells, are crucial for neuronal health, learning and memory ...
(2019-07-05)Brassinosteroids are a class of plant hormones critical for control of growth and development. While the signaling pathway through which brassinosteroid signals are processed has been the subject of intense study for the ...