Center for Biophysics and Computational Biology
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(2018-07-06)Protein folding, a ubiquitous and vital biological process, where protein random coil transforms into certain conformation in order to fulfill its function. Misfolded protein which fails to acquire proper shape, not only ...
(2017-11-30)Membrane proteins are proteins either embedded or located at the peripheral of the biological membrane. The functions of membrane proteins include importing/exporting ions/small molecules into/output of the cell, cellular ...
Theoretical and computational investigations into structure-function relationships of biomolecular machines at atomic resolution (2017-07-14)Molecular machines play vital roles in many cellular processes, including DNA replication and repair, gene expression, protein degradation, protein secretion and maintenance of pH homeostasis. Despite intense research ...
(2017-05-26)Many cellular functions rely on the movements of molecular motors. Single molecule studies of these motors allow investigation into their step-sizes and stall forces. Such studies inevitably involve noise, which is inherent ...
Molecular insights into the mechanisms of transport and energy coupling in membrane transport proteins (2017-07-13)Membrane transport proteins are the main gatekeepers controlling the traffic of molecules in and out the cell. The mechanism by which they mediate selective and regulated transport across the membrane is of broad physiological ...