# Browse Center for Biophysics and Computational Biology by Subject "Biophysics, Medical"

• (1994)
In biological systems, DNA/RNA-protein interactions as well as drug-DNA interactions play important roles in genetic processes. A fundamental understanding of these processes requires a detailed structural knowledge of ...

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• (1995)
Magnetic resonance (MR) is a rapidly growing versatile and non-destructive tool for investigation of various aspects of biochemistry, physiology and disease. It is valuable to evaluate the new MR techniques and apply them ...

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• (1993)
Guinea pig left atria were suspended in a tissue bath of normal Krebs-Henseleit solution which was aerated with 95% O$\sb2$/5% CO$\sb2$ and maintained at 27$\sp\circ$C. The atria were attached to a force transducer and ...

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• (2004)
Near infrared spectroscopy (NIBS) has been used for determination of tissue optical properties. This technique has been especially useful for in vivo monitoring of hemodynamics and oxygen saturation in tissue. For this ...

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• (2009)
Mechanical proteins perform a vital role in cells by transmitting and bearing mechanical forces involved in cell growth, locomotion, and adhesion. Little is known at the molecular level that explains how such proteins are ...

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• (1994)
Magnetic Resonance Imaging (MRI) holds enormous potential for exploring the functional centers of a living brain in vivo. Among the MRI techniques a number of different approaches have provided initial success. The focus ...

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• (1988)
The site of ultrasonic absorption in suspensions of negatively-charged large unilamellar vesicles (LUVs) was investigated. The ultrasonic absorption per wavelength, $\alpha\lambda$, was determined for suspensions of LUVs ...

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• (1989)
The pH of the tumor microenvironment may be important in assessment of response to hyperthermic therapy. Little clinical in vivo data is available during such therapy due to the inherent limitations of the microelectrode ...

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• (1993)
In this thesis, the electron paramagnetic resonance (EPR) methods for simultaneous measurement of intra- and extracellular concentration of oxygen ( (O$\sb2$)) in viable cells have been developed.

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• (1979)

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• (2006)
For decades there has only been anecdotal data regarding how difficult it is to crystallize membrane proteins but these facts are never rigorously evaluated, because virtually no one can report all the reasons why membrane ...

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• (1996)
Chemotherapy with anticancer drugs is one of the main method of cancer treatment. The exploitation of the stereochemical interactions between anticancer drugs and DNA is of great importance for the ultimate clinical advances ...

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• (1995)
There has been a growing interest, in recent years, in the measurement of diffusion of water and metabolites in living systems by magnetic resonance (MR) techniques. Knowledge of the diffusion coefficients of the molecules ...

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• (1991)
The multicellular spheroid embodies many of the physiological and anatomical characteristics of in vivo tumors and provides an appropriate context for investigating the phenomenon of reoxygenation and the interplay of local ...

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• (2008)
Finally, we have demonstrated that the fluorescein encapsulated one micron liposomes can be used to detect inorganic mercury in water. At the same time, we have shown that chelators of inorganic mercury can be encapsulated ...

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• (1991)
This thesis aims to demonstrate the usefulness of Nuclear Magnetic Resonance Spectroscopy in understanding normal human placental and uterine metabolism as well as its application in the study of gestational and gynecological ...

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• (1996)
The techniques of magnetic resonance (MR) imaging and spectroscopy have recently garnered much attention as tools for detecting and localizing metabolic changes in living tissues in various pathologic states and during ...

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• (1999)
A pulse method of blocker-induced noise analysis was used to study the time-dependent changes of channel density (NT), channel open probability (Po) and single-channel current (iNa) of apical membrane epithelial Na + ...

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• (1994)
Unusual DNA sequences are known to adopt interesting three-dimensional structures which might have important biological roles. For my thesis, I have tried to study the influence of various degrees of perturbations of DNA ...

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• (1989)
I. Three kinds of monoclonal antibodies have been found against iodopsin and other cone pigments in chicken retina: (1) specifically against iodopsin (cell line of 7D3); (2) against iodopsin and another cone pigment (cell ...

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