# Browse Dissertations - Biophysics and Computational Biology by Title

• (1979)

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• (2011-08-26)
Malaria, caused by Plasmodium spp., causes ~1 million deaths each year and there are ever present problems due to drug resistance. In this work, I used drug-repositioning strategy with bisphosphonates to discover a lead ...

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PDF (19MB)
• (1977)

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• (2002)
This thesis research uses single molecule spectroscopy to study the dynamics of hairpin ribozyme---an enzymatic RNA molecule capable of cleaving phosphodiester linkage. RNA controls key processes of gene expression. Ribozymes ...

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• (1995)
Oxygen quenching of tryptophan fluorescence in a number of globular proteins provided some of the early experimental evidence for conformational fluctuations in proteins. Gratton et al. (Biophysical J. 1984. 45:789-794) ...

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• (1977)

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• (1996)
The ultrasonic speed and attenuation coefficient of three muscle samples were measured in-vitro as a function of temperature and frequency. The sarcomere length of each of these samples was also determined. The three muscle ...

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• (2004)
Natural auditory scenes, like frog choruses, comprise multiple sound sources like individual vocalizations and background noise that overlap in the time- and frequency domains. Detection of sound in such a background is ...

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• (1994)
$\rm O\sp6$-ethyl-G $\rm (e\sp6G)$ is a persistent alkylation lesion of DNA, caused by the exposure of cells to alkylating agents such as N-ethyl-N-nitrosourea. Alkylating N-nitroso compounds are extremely significant as ...

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PDF (6MB)
• (1998)
The specific recognition between biological molecules has been widely exploited in many applications in medicine, biology, and biotechnology. These applications range from biosensors to affinity chromatography. However, ...

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• (1994)
Using pregermination plant seeds as a model for proliferative tissue, we have investigated the effects of gamma radiation and hyperthermia on barley and alfalfa. Barley seeds soaked for up to 16h prior to irradiation were ...

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• (1968)

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• (2000)
This work describes the development of a technique for high-resolution patterning of proteins or biomolecules on glass substrates for the localization of neurons and their axons and dendrites. The new patterning process ...

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PDF (8MB)
• (1978)

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PDF (9MB)
• (1988)
The concentration of molecular oxygen within cells plays a crucial role in many physiological and pathological processes. There are, however, very few data on actual intracellular oxygen concentrations, due largely to the ...

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PDF (6MB)
• (1979)

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PDF (4MB)
• (1986)
The dissertation research was the characterization of photoinduced electron transfer in the reaction center protein involved in bacterial photosynthesis of the species Rhodopseudomonas viridis. The quinone acceptor complex ...

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• (1997)
H252Q and six donor-side mutants became the important tools to investigate a new model of neutral tyrosine radical, $\rm Y\sb{Z}\sp\cdot,$ introduced by Gilchrist et al. (1995) and Hoganson et al. (1995). In this new model, ...

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• (1984)
The electron transfer reactions of the ubiquinol:cytochrome c(,2) oxidoreductase (b-c(,1) complex) of the photosynthetic bacteria Rps. sphaeroides have been investigated through the use of optical spectroscopy and chemical ...

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PDF (11MB)
• (2002)
Synechocystis 6803 cytochrome cM were purified and its physical and structural characteristics investigated. Highly purified cytochrome cM was obtained in oligomeric forms. Our spectroscopy data indicate that the 6th axial ...

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PDF (16MB)