# Browse Dissertations - Biophysics and Computational Biology by Title

• (1996)
Two peaks consistently arise near 1.3 ppm in $\sp1$H NMR spectroscopic studies of fatiguing skeletal muscles. They are typically 15-20 Hz apart at 300 MHz. Known resonances in this region include lactate, alanine, threonine, ...

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• (2013-05-24)
Noncommunicable diseases (NCD) are currently the leading cause of death worldwide. Over 57 million deaths occur globally each year, with close to 36 million of them attributed to NCD’s, and 80% of those in low and middle ...

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• (1988)
The site of ultrasonic absorption in suspensions of negatively-charged large unilamellar vesicles (LUVs) was investigated. The ultrasonic absorption per wavelength, $\alpha\lambda$, was determined for suspensions of LUVs ...

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• (2008)
The dissertation is concerned with biophysical applications of Forster resonance energy transfer (FRET) and development and application of fluorescence lifetime-resolved imaging microscopy (FLIM). It includes work to extend ...

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• (1989)
The pH of the tumor microenvironment may be important in assessment of response to hyperthermic therapy. Little clinical in vivo data is available during such therapy due to the inherent limitations of the microelectrode ...

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• (1993)
In this thesis, the electron paramagnetic resonance (EPR) methods for simultaneous measurement of intra- and extracellular concentration of oxygen ( (O$\sb2$)) in viable cells have been developed.

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• (1992)
Bicarbonate-reversible inhibition of the electron acceptor side of photosystem II (PS II), but not of photosynthetic bacteria, has been known for a long time. In formate treated thylakoids, the (Q$\sb{\rm A}\sp-$) decays ...

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• (1991)
Motions in proteins are often an important part of their function. Structural information about the protein is hence incomplete without an understanding of the protein dynamics. X-ray crystallography is the technique used ...

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• (1994)
Improvements in the information content of nuclear magnetic resonance (NMR) images have recently been sought through the development of new contrast mechanisms for magnetic resonance imaging (MRI) and NMR microscopy. This ...

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• (2013-05-24)
Although it is known that single-stranded DNA binding proteins (SSB) can stimulate helicase activity, the mechanism by which this occurs may be more complex than sequestering ssDNA products of duplex separation. Here, ...

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• (2009)
Retinal Protonated Schiff Base (RPSB) is the chromophore employed by the rhodopsin family of proteins, which includes rhodopsin (Rh), bacteriorhodopsin (bR) and halorhodopsin (hR). Photoisomerization of RPSB from the ...

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• (2012-02-06)
Domain-based approaches are used in phylogenetic reconstruction and functional identification. Two groups of ionotropic glutamate receptors (iGluR’s) were identified with the topology of the binding core and pore-loop of ...

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• (1979)

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• (2011-08-26)
Malaria, caused by Plasmodium spp., causes ~1 million deaths each year and there are ever present problems due to drug resistance. In this work, I used drug-repositioning strategy with bisphosphonates to discover a lead ...

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• (1977)

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• (1995)
Oxygen quenching of tryptophan fluorescence in a number of globular proteins provided some of the early experimental evidence for conformational fluctuations in proteins. Gratton et al. (Biophysical J. 1984. 45:789-794) ...

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• (1977)

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• (1996)
The ultrasonic speed and attenuation coefficient of three muscle samples were measured in-vitro as a function of temperature and frequency. The sarcomere length of each of these samples was also determined. The three muscle ...

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• (1994)
$\rm O\sp6$-ethyl-G $\rm (e\sp6G)$ is a persistent alkylation lesion of DNA, caused by the exposure of cells to alkylating agents such as N-ethyl-N-nitrosourea. Alkylating N-nitroso compounds are extremely significant as ...

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• (1994)
Using pregermination plant seeds as a model for proliferative tissue, we have investigated the effects of gamma radiation and hyperthermia on barley and alfalfa. Barley seeds soaked for up to 16h prior to irradiation were ...

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