# Browse Dissertations - Biophysics and Computational Biology by Title

• (2005)
A new design for the detection of mid-infrared and near-infrared transient spectra is presented. In this setup, time-varying IR spectra with 150 nanoseconds time resolution can be collected in a single sweep up to several ...

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• (2004)
Cargo transportation within a cell is accomplished by processive molecular motors. Motor proteins haul the cargo and transport it over long distances by taking hundreds of consecutive steps without dissociating from the ...

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• (1968)

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• (1968)

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• (2007)
Finally, we used a single molecule fluorescence quenching assay to study the timing of the neck linker conformational change that occurs as kinesin walks processively along a microtubule. We observed repetitive, alternating ...

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• (2003)
Complete prediction of the folding processes for complex protein molecules through first principles is currently not possible (2003). Here we take an empirical approach towards a better understanding of the protein-folding ...

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• (1975)

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• (2008)
Fourier Transform Infrared Spectrsocopy (FTIR) is a powerful technique that is well suited to the investigation of protonation/deprotonation reactions of individual side chains within proteins, as well as any changes that ...

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• (1989)
In this thesis, Fourier Transform Infrared Spectroscopy (FTIR) was used to study the interaction between the protein myoglobin (Mb), and substrate carbon-monoxide (CO), as a model system of control in protein-ligand ...

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• (1993)
Fusinite, an inertinite coal maceral, exhibits a symmetric and exchange-narrowed electron paramagnetic resonance (EPR) line (g = 2.00276), with a first derivative peak-to-peak linewidth $(\Delta$B) which is reversibly ...

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• (1983)
The binding of ligands to heme proteins has been studied extensively in the past. A sequential barrier model was postulated. Using flash photolysis, various aspects of the model are studied in this work to give a better ...

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• (1999)
The vestibular-ocular reflex (VOR) is a plastic system found in vertebrates which produces eye rotations that compensate for head rotations. Simultaneous motion and vision are thus possible since the reflex keeps vision ...

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• (2011-05-25)
“Head-to-head” terpene synthases catalyze the first committed steps in sterol and carotenoid biosynthesis: the condensation of two isoprenoid diphosphates to form cyclopropylcarbinyl diphosphates, followed by ring opening. ...

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• (2007)
In this work we characterize the sequence diversity of the heme-copper oxidoreductase superfamily by analyzing over 1100 microbial genomes (Bacteria and Archaea) and nine microbial environmental metagenomic datasets. Over ...

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• (2006)
For decades there has only been anecdotal data regarding how difficult it is to crystallize membrane proteins but these facts are never rigorously evaluated, because virtually no one can report all the reasons why membrane ...

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• (2013-05-24)
Many types of diseases including cancer and autism are associated with copy-number variations in the genome. Most of these variations could not be identified with existing sequencing and optical DNA mapping methods. We ...

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• (1996)
Chemotherapy with anticancer drugs is one of the main method of cancer treatment. The exploitation of the stereochemical interactions between anticancer drugs and DNA is of great importance for the ultimate clinical advances ...

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• (1990)
Hydroperoxide is required to activate prostaglandin endoperoxide synthase (PES) cyclooxygenase by formation of an enzyme-radical species (derived from a PES peroxidase intermediate), and is generated by the cyclooxygenase ...

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• (1958)

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• (1992)
Melanins are complex, incompletely understood polymeric pigments which uniquely contain a stable population of organic free radicals amenable to study by electron paramagnetic resonance (EPR, or equivalently, electron spin ...

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