# Browse Dissertations - Biophysics and Computational Biology by Title

• (1990)
The work presented in this thesis is among the first efforts to study the mechanism of electron transfer through b/c$\sb1$ complex of R. sphaeroides under the coupled conditions. It aims at (1) establishing a kinetic model ...

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• (1989)
The main aim of the project is to investigate the characteristics of the secondary plastoquinone, Q$\sb{\rm B}$, and its semiquinone, Q$\sb{\rm B}\sp-$, in the Q$\sb{\rm B}$ binding site and to characterize the two electron ...

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• (1965)

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• (2002)
SAR/MAR sequences have been hypothesized as forming the bases of DNA loops in metaphase chromosomes. To test the structural role of SAR/MAR sequences, we created stable cell lines containing chromosomes with regions of ...

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• (2012-05-22)
Molecular dynamics (MD) is a computational method employed for studying the dynamics of nanoscale biological systems on nanosecond to microsecond timescales. Using MD, researchers can utilize experimental data from ...

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• (2009)
The first molecular dynamic simulations of the interaction of cyt c and yeast bc1 complex are described. Contrary to results from crystallographic studies, the simulations reveal multiple dynamic hydrogen bonds and salt ...

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• (1981)
The moments of the time constant density function, as measured by quasi-elastic light scattering and Koppel's method of cumulants, are expressed in terms of moments of the size density function of single-walled hollow ...

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• (1990)
This thesis is a report on photocurrent measurements of purple membrane oriented in an polyacrylamide gel. In the first section, the photocurrent measuring system was frequency analyzed from DC to 100 MHz. The optimized ...

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• (1970)

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• (2012-06-27)
Neuropeptides, as one largest category of cell-to-cell signaling molecules, play a regulatory role in a range of physiological and behavioral functions within an organism, such as reproduction, feeding, metabolism regulation, ...

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• (1969)

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• (1995)
There has been a growing interest, in recent years, in the measurement of diffusion of water and metabolites in living systems by magnetic resonance (MR) techniques. Knowledge of the diffusion coefficients of the molecules ...

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• (1991)
The multicellular spheroid embodies many of the physiological and anatomical characteristics of in vivo tumors and provides an appropriate context for investigating the phenomenon of reoxygenation and the interplay of local ...

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• (1993)
A mathematical model has been developed to investigate the time course of ion and water transport across airway epithelia. Model variables were intracellular and apical concentrations of sodium, potassium, chloride; apical, ...

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• (2014-01-16)
Living cells have evolved specialized transport proteins called membrane transporters and channels that catalyze exchange of materials across the cell membrane. Membrane trans- porters couple the active transport of their ...

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PDF (40MB)
• (2001)
A preliminary characterization of the structure of membrane supported C-cadherin monolayers, that are used in the surface force measurements, is presented in the latter part of the thesis. Using ellipsometry, we monitor ...

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• (2014-09-16)
Isoprenoids (or terpenes) are a large class of compounds with great physiological importance in all kingdoms of life. The research in this work explored the mechanism and inhibition of several enzymes in two important ...

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• (2012-06-27)
The methylerythritol phosphate pathway (also known as the non-mevalonate pathway) of isoprenoid biosynthesis is potentially an important anti-bacterial and anti-malarial drug target. However, the catalytic mechanisms of ...

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• (1974)

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• (2013-08-22)
ATP-binding cassette (ABC) transporters are a superfamily of primary membrane transporters that are abundant yet highly diverse in structures and functions. These proteins power the active transport of a large variety of ...

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PDF (86MB)