RNA sequencing (RNA-seq) is one of the most common technologies in use today for the analysis of gene expression and transcriptome variation in biological samples (Zhong Wang et al. 2009). As of 2011, the NCBI Sequence ...

The standard approaches to lead identification and optimization involve a long and expensive process including random and nonrandom (targeted or focused) screening. Given the limited success of these standard approaches, ...

Many cellular functions rely on the movements of molecular motors. Single molecule studies of these motors allow investigation into their step-sizes and stall forces. Such studies inevitably involve noise, which is inherent ...

Photosystem II (PS II) is a polypeptide complex which operates in series with the cytochrome $b/f$ complex and photosystem I to perform light-driven transport of electrons from H$\sb2$O to NADP and of protons from the ...

This dissertation describes the process of optimizing a Fluorescence Lifetime Imaging Microscopy (FLIM) system in order to observe the dynamics of enzymes in live cancer cells. The enzyme studied throughout this research ...

The intent of this research was the development and use of parallel instrumentation for the study of the bioenergetics of photosynthesis in in vitro and intact plant systems. To this end, three instruments have been developed ...

A core conductor analysis was applied to the passive relaxation of the transmembrane potential in response to 20 ms pulses of current in luminosity-type and chromaticity-type horizontal cells. The time course of the ...

This thesis aims to demonstrate the usefulness of Nuclear Magnetic Resonance Spectroscopy in understanding normal human placental and uterine metabolism as well as its application in the study of gestational and gynecological ...

Oxygenic photosynthesis converts light-energy into chemical free energy by reducing NADP$\sp+$ to NADPH and producing ATP. Eukaryotic plants and algae as well as prokaryotic cyanobacteria and prochlorophytes have a similar ...