# Browse Dissertations - Biophysics and Computational Biology by Title

• (2014-09-16)
The information that instructs cells on how to create the molecules that perform cellular functions resides within the DNA. The basic unit of genetic information is called a gene, which is a region of the DNA that contains ...

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• (1996)
The techniques of magnetic resonance (MR) imaging and spectroscopy have recently garnered much attention as tools for detecting and localizing metabolic changes in living tissues in various pathologic states and during ...

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• (1990)
The kinetics and thermodynamics of the high potential chain in the chromatophores from Rhodobacter sphaeroides have been reexamined. It was found that RC, cyt c$\sb2$ and c$\sb1$ after a flash reached a state not far from ...

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• (1970)

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• (2011-01-14)
Two-photon (2P) excited fluorescence microscopy is particularly advantageous for imaging biological specimens since it offers reduced scattering, deep sample penetration, and intrinsic confocality when excited with point ...

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• (1990)
The problem of protein dynamics is introduced and its significance explained. Properties of the oxygen-storage protein myoglobin (Mb) as a model system for dynamics studies are discussed. Special attention is paid to Mb's ...

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• (1970)

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• (1979)

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• (2002)
Functional compartmentation of anaerobic metabolism was demonstrated in intact tissue. Force-independent ATP utilization, primarily the Ca 2+ pump of the sarcoplasmic reticulum, preferentially uses ATP derived from ...

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• (2015-01-21)
In eukaryotic cells, the genome is packed into fundamental units called nucleosomes, where 147 base pairs of DNA are wrapped around a protein core. Stable packing of DNA in nucleosomes imposes a barrier for accessibility ...

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• (1999)
A pulse method of blocker-induced noise analysis was used to study the time-dependent changes of channel density (NT), channel open probability (Po) and single-channel current (iNa) of apical membrane epithelial Na + ...

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• (1997)
The mechanisms of proton release and uptake in bacteriorhodopsin (bR) were investigated using steady state and kinetic spectrophotometry and photocurrent methods. First, a kinetic model for the formation of the crucial M ...

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• (1967)

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• (1958)

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• (1991)
Rhodopsin is the light-sensitive pigment of the photoreceptor cells of higher organisms. Photon absorption by rhodopsin initiates a biochemical amplification cascade that results in an electrical signal. Rhodopsin is ...

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• (2001)
Intracellular calcium regulates multiple processes in all cells, including contraction in myocytes. In smooth muscle the primary signal transduction cascade for agonist activation is receptor → G-protein → ...

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• (1977)

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• (1996)
Heme proteins are ubiquitous in biological systems and it is of interest to understand how the structure of various heme proteins determines their respective biological function. Using site-directed mutagenesis, the amino ...

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• (2010)
Finally, ongoing work is presented on the role of ribosomal signatures in the first steps of ribosomal assembly. Ribosomal signatures are features that are completely conserved within one domain of life but absent from the ...

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• (2010-05-14)
Translation, the process of reading genetic information and synthesizing the corresponding proteins, is universal and found throughout the three domains of life. The flow of information in translation involves a series of ...

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