Dept. of Cell and Developmental Biology
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(2015-02-24)Lanthipeptides are a family of ribosomally synthesized and posttranslationally modified natural products defined by the characteristic thioether crosslinks lanthionine and methyllanthionine. Among the various biological ...
(2015-01-21)Molecular chaperones have evolved to support the general stability and maintenance of the cellular proteome. Through their broad binding capacity, transient interactions, and high cellular abundance, the Hsp70 and Hsp90 ...
(2015-01-21)The mammalian cell nucleus is a complex yet highly organized structure. There is significant amount of knowledge about the organization of nucleus; however, the influence of such structural complexity of the nucleus in ...
(2015-01-21)Cellular and developmental processes are regulated by extracellular and intracellular signals that are mediated by networks of signaling pathways. In recent years, microRNAs have also emerged as a class of critical modulators ...
(2015-01-21)Much remains to be understood regarding the molecular mechanisms controlling stem cell fate. Through studies in human pluripotent stem cells (hPSCs), I have identified SGK196, an atypical kinase of relatively unknown ...