Dept. of Cell and Developmental Biology
Browse Collections of Items
(2015-07-09)Human embryonic stem cell (hESC) research provides promising prospects for the future of regenerative medicine. To fully realize its potentials, we not only need to further our understandings toward the molecular mechanisms ...
(2015-07-14)Mammalian cells use a variety of molecules to receive, process, and transmit information from the extracellular environment. Proteins receive and transmit signals through direct protein-protein interaction at the membrane ...
Mammalian TIMELESS and Protein Kinase G: Partners Linking the Molecular Clockwork to Environmental Light (2004)Research in our lab has determined that GLU activates Protein Kinase G (PKG), and that this activation is required for the mammalian GLU-induced phase advance. Since the Drosophila phase advance proceeds through ...
(2004)These data indicate that mTim is required for rhythmicity and is a functional homolog of dTim on the negative feedback arm of the mammalian molecular clockwork. This models supports conservation of transcriptional elements ...
Estradiol Regulation of Leucine-Rich Repeat Immunoglobulinlike Domains Protein 1 (Lrig 1) and Roles of Estrogen Receptor in Translational Regulation in Breast Cancer Cells (2010)The effects of estradiol on cellular function are pleiotropic. As a transcriptional regulator, ER regulates many genes that can have a subsequent impact on other cellular functions. These so-called secondary effects are ...