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Browse Dept. of Microbiology by Contributor "Joanna Shisler"
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Characterization of the Anti-Inflammatory Effects of the Molluscum Contagiosum Virus MC160 Protein (2008)Using a series of MC160 deletion mutant proteins, we found that two distinct regions of the MC160 protein independently inhibit TNF-mediated NF-kappaB activation. Specifically, we observed that the second DED of MC160 ...
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(2010)This dissertation elaborates on M2's molecular functioning as a viral immunomodulator to inhibit both the ERK1/2 and NF-kappaB pathways, which is reliant on its glycosylation status and proper cellular trafficking within ...
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