The sequestration of essential nutrients from pathogens is a key component in the vertebrate immune response. One aspect of this defense, known as nutritional immunity, is the sequestration of the essential metals manganese ...

Escherichia coli resides in the lumen of the gut, where it encounters both biotic and abiotic sources of hydrogen peroxide stress. Hydrogen peroxide (H2O2) diffuses into cells, where it reacts with iron via Fenton chemistry. ...