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Browse Dept. of Microbiology by Contributor "Mitchell, Douglas A"
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(2021-03-02)YcaO enzymes are best known to catalyze the ATP-dependent peptide backbone activation and subsequent formation of azoline heterocycles. It has been proposed that YcaO enzymes can also install lactamidines and thioamides ...
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(2015-07-15)Natural products continue to be an important source of therapeutically-relevant compounds. With the advent of inexpensive genome sequencing it has become apparent that bacteria produce a larger array of natural products ...
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(2015-11-30)Bacteria are a fruitful source of metabolites, many of which have been the scaffolds for the majority of approved antibiotic compounds. In this dissertation, I present the discovery and characterization of a bacterial ...
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