Toll-like receptors (TLRs) are central receptors of the innate immune system which drive host inflammation and adaptive immune responses upon detection of invading microbes. Drugs targeting TLRs are of considerable interest ...

The covalent attachment of lipoic acid to the lipoyl domains (LDs) of the central metabolism enzymes pyruvate dehydrogenase (PDH) and oxoglutarate dehydrogenase (OGDH) is essential for their activation and thus for respiratory ...

Bacteroides spp. are a primary inhabitant of the human colon, and play an important role in the health of the human host as Bacteroides are important for nutrient acquisition, the breakdown of starches that would otherwise ...