Thiamine (vitamin B1) is an essential cofactor for all organisms. Humans primarily acquire thiamine through their diet and thiamine deficiencies have adverse neurological effects. However, the role gut microbes play in ...

Escherichia coli resides in the lumen of the gut, where it encounters both biotic and abiotic sources of hydrogen peroxide stress. Hydrogen peroxide (H2O2) diffuses into cells, where it reacts with iron via Fenton chemistry. ...