# Browse Dissertations and Theses - Pathobiology by Title

• (1994)
Pseudorabies (PrV) is an alphaherpesvirus disease of swine. The lungs are a main site of viral replication and alveolar macrophages (PAM) are productively infected. Programs for the eradication of PrV are currently underway ...

application/pdf

PDF (5MB)
• (2014-01-16)
Occupational and environmental pulmonary exposure to carbon nanotubes (CNT) is considered to be a health risk with a very low threshold of tolerance as determined by the Center for Disease Control. Cell lines exposed to ...

application/pdf

PDF (4MB)
• (1990)
Current antimicrobial susceptibility testing methods do not assess the influence of host defenses, the dynamics of drug disposition, or the interaction between changing drug concentrations and a bacterium in a host ...

application/pdf

PDF (5MB)
• (1989)
Neutrophil function was evaluated in vitro 24 and 48 hours after administration of a single IV dose of dexamethasone sodium phosphate (0.088 mg/kg) to adult horses. Neutrophils were separated from whole blood using a ...

application/pdf

PDF (5MB)
• (2012-09-18)
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is a 15Kb enveloped positive-sense, single stranded RNA virus. More than two decades after the emergence of PRRSV, much is known about the viral genome, spread, ...

application/pdf

PDF (3MB)
• (1997)
Studies of the regulatory idiotypic network have routinely assayed idiotypic (Ab1) and anti-idiotypic (Ab2) levels in the immune response. This work is a follow up of a previous study in which Ab1 and Ab2 responses to the ...

application/pdf

PDF (5MB)
• (2019-07-12)
Fungi are emerging as significant pathogens of multiple taxa. In addition to the impact of Ophidiomyces ophiodiicola on snakes, Batrachochytrium dendrobatidis (chytrid) has been linked to massive declines in amphibian ...

application/pdf

PDF (3MB)
• (2003)
The emergence of several diseases affecting amphibian populations worldwide has prompted investigations into factors that determine the distribution and abundance of parasites in frogs. Environmental and land use determinants ...

application/pdf

PDF (10MB)
• (1989)
Three data sources were combined to examine spatial and individual risk factors for anaplasmosis, an economically significant, blood-borne infection of ruminants. A survey of 220 Illinois veterinarians identified a ...

application/pdf

PDF (13MB)
• (1994)
Molecular diagnostic tests to detect ovine lentivirus (OLV) infected sheep were developed and validated and then applied to study the epidemiology and production impacts of natural OLV infection in flocks at the U.S. Meat ...

application/pdf

PDF (13MB)
• (2000)
The second study used a deterministic dynamic computer simulation model of the transmission of T. gondii in the swine farm ecosystem in a factorial experimental design to test the following hypotheses. T. gondii infection ...

application/pdf

PDF (4MB)
• (2017-07-14)
Canine central nervous system tumors can develop deeply within the brain parenchyma, precluding surgical resection and limiting therapeutic options. PAC-1 is a novel, blood-brain barrier penetrant, pro-apoptotic small ...

application/pdf

PDF (4MB)
• (2014-05-30)
Biologically relevant cell culture assays that can be adapted for high-throughput screening are very important for biopharmaceutical industry. Cellular material for such applications can represent static cultures that do ...

application/pdf

PDF (3MB)
• (2005)
In summary, this work provides information to understand the isoprenoid pathway in T. gondii by isolation and characterization of an important enzyme in the pathway, TgFGGPS. Identification of TgFGGPS as the molecular ...

application/pdf

PDF (3MB)
• (2005)
We have purified from bovine colostrum digests an unsaturated fatty acid that inhibits Cryptosporidium parvum sporozoite invasion of host cells in vitro. A panel of similar lipids with varying chain lengths and degrees of ...

application/pdf

PDF (5MB)
• (1997)
Temperature is the only environmental stimulus currently known to affect K1 capsule expression. Capsule is maximally expressed at body temperature (37$\sp\circ$C or 98.6$\sp\circ$F), but is turned off at temperatures ...

application/pdf

PDF (5MB)
• (2004)
We found that the composition of the adjuvant used to induce EAE had important implications on the degree of genetic susceptibility necessary to result in disease. We also found that of the many quantitative trait loci ...

application/pdf

PDF (7MB)
• (2001)
Additional studies identified phenotypic-specific effects of QTL on AOD. Interaction analysis showed that multiple loci may affect a particular phenotype including loci linked to other phenotypes and suggested that some ...

application/pdf

PDF (5MB)
• (2007)
Colon cancer is one of the leading causes of cancer deaths in the United States and increasing in incidence globally. Grape seed extract (GSE) is a nutritional supplement with claims as a chemopreventive compound. Preliminary ...

application/pdf

PDF (4MB)
• (1992)
Phosphorylation of proteins at tyrosine is an important mechanism for regulating cell growth and proliferation in metazoan organisms. This phosphorylation is conducted by a tyrosine-specific protein kinase. The activation ...

application/pdf

PDF (4MB)