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Computational studies of the effect of rotation on convection during protein crystallization

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Title: Computational studies of the effect of rotation on convection during protein crystallization
Author(s): Bhattacharjee, Pratik; Riahi, Daniel N.
Subject(s): boundary layers convection flow instability geophysical fluid dynamics materials processing multiphase flows nonlinear waves turbulence physics
Abstract: Effect of rotation on nonlinear solutal convection during protein cystallization is modelled and studied computationally under both normal and microgravity conditions. The axis of the externally imposed rotation, which is assumed to be either parallel or antiparallel to the gravity vector, is assumed to be inclined at an angle γ with respect to the axis of the crystal. In addition to the angle γ, the significant parameters are the solutal Grashof number G(r), representing the buoyancy effect and the Taylor number T(a) representing the rotational effect. The numerical computations for various values of the parameters and the gravity level indicated non-trivial competing effects, due to buoyancy, centrifugal and Coriolis forces, on the convective flow adjacent to the crystal interface and the associated solute flux. In particular, certain regimes in (T(a), γ)-space were detected where the Sherwood number, representing the convective solute flux, and the convective effects are noticably reduced. These results can provide conditions under which convective transport during the protein crystal growth approaches the diffusion limited transport, which may be desirable for the production of higher quality protein crystals.
Issue Date: 2003-02
Publisher: Department of Theoretical and Applied Mechanics (UIUC)
Series/Report: TAM Reports 1013
Genre: Technical ReportArticle
Type: Text
Language: English
URI: http://hdl.handle.net/2142/282
ISSN: 0073-5264
Publication Status: published or submitted for publication
Peer Reviewed: is peer reviewed
Date Available in IDEALS: 2007-03-08
Is Version Of: Published as: P. Bhattacharjee and D. N. Riahi. Effect of rotation on surface tension driven flow during protein crystallization. Microgravity Science and Technology, v 14, n 4, 2003, p 36-44. Copyright 2003 Z-Tec Publishing, Bremen, Germany.
 

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  • Theoretical and Applied Mechanics (TAM) Technical Reports
    TAM technical reports include manuscripts intended for publication, theses judged to have general interest, notes prepared for short courses, symposia compiled from outstanding undergraduate projects, and reports prepared for research-sponsoring agencies.

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