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Effect of rotation on surface tension driven flow during protein crystallization

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Title: Effect of rotation on surface tension driven flow during protein crystallization
Author(s): Bhattacharjee, Pratik; Riahi, Daniel N.
Subject(s): boundary layers convection flow instability geophysical fluid dynamics materials processing multiphase flows nonlinear waves turbulence physics
Abstract: Effect of rotation on surface tension gradient driven flow, which is also known as Marangoni convective flow, during protein crystallization is modelled and studied computationally under microgravity conditions, where the surface tension gradient force is the main significant driving force. The axis of the externally imposed rotation, which is assumed to be either parallel or anti-parallel to the gravity vector, is assumed to be inclined at an angle γ with respect to the axis of the crystal. In addition to the angle γ, the main parameters are the solutal Marangoni number M(c), representing the surface tension gradient force and the Taylor number T(a) representing the rotational effect. The numerical computations for various values of the parameters and low gravity levels indicated nontrivial competing effects, due to surface tension gradient, centrifugal and Coriolis forces, on the flow adjacent to the protein crystal interface and the associated solute flux. In particular, for given values of M(c), certain values of T(a) were detected where the Sherwood number, representing the convective solute flux, and the convective flow effects are noticeably reduced. These results can provide conditions under which convective flow transport during the protein crystallization approaches the diffusion limited transport, which is desirable for the production of higher quality protein crystals.
Issue Date: 2003-05
Publisher: Department of Theoretical and Applied Mechanics (UIUC)
Series/Report: TAM Reports 1020
Genre: Technical Report
Type: Text
Language: English
URI: http://hdl.handle.net/2142/290
ISSN: 0073-5264
Publication Status: published or submitted for publication
Peer Reviewed: is peer reviewed
Date Available in IDEALS: 2007-03-08
Is Version Of: Published as: P. Bhattacharjee and D. N. Riahi. Effect of rotation on surface tension driven flow during protein crystallization. Microgravity Science and Technology, vol.14, no.4, p 36-44 (2003). Copyright 2003 Z-Tec Publishing, Bremen, Germany.
 

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  • Theoretical and Applied Mechanics (TAM) Technical Reports
    TAM technical reports include manuscripts intended for publication, theses judged to have general interest, notes prepared for short courses, symposia compiled from outstanding undergraduate projects, and reports prepared for research-sponsoring agencies.

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