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Studies towards understanding the function of LanCL1

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Title: Studies towards understanding the function of LanCL1
Author(s): Koh, Tong Hee
Advisor(s): van der Donk, Wilfred A.
Department / Program: Biochemistry
Discipline: Biochemistry
Degree Granting Institution: University of Illinois at Urbana-Champaign
Degree: M.S.
Genre: Thesis
Subject(s): LanCL1 protein-protein interaction apoptosis oxidative stress knockout mouse
Abstract: LanC-like protein 1 (LanCL1) is a eukaryotic homolog of bacterial protein LanC. Unlike the well studied LanC proteins, the functions of LanC-like proteins are yet unknown. To investigate the function of LanCL1 several studies were undertaken. Proteins interacting LanCL1 were tried to be found but were not accomplished. Also, the role of LanCL1 in apoptosis and oxidative stress were hypothesized, but the studies indicated no correlation. Finally, LanCL1 knockout mice were generated for further investigation.
Issue Date: 2012-05-22
Rights Information: Copyright 2012 Tong Hee Koh
Date Available in IDEALS: 2012-05-22
Date Deposited: 2012-05

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