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Title:A Computational - Experimental Study of Small Globular Proteins
Author(s):Larios, Edgar
Doctoral Committee Chair(s):Martin Gruebele
Department / Program:Physics
Discipline:Physics
Degree:Ph.D.
Genre:Dissertation
Subject(s):Hyperfluorescent proteins
ubiquitin mutants
partially folded proteins
Abstract:The folding of small globular proteins is studied using a combination of experimental and computational techniques. The use of several experimental probes to study the formation of secondary and tertiary structure of proteins is stressed to obtain a description of their folding. Molecular dynamics simulations are carried out under non-physiological conditions to overcome experimental obstacles. Under physiological conditions, the combination of molecular dynamics and experiments resolves the folding of small proteins in great detail.
Issue Date:2005-05
Genre:Dissertation / Thesis
Type:Text
Language:English
URI:http://hdl.handle.net/2142/34778
Rights Information:©2005 Edgar Larios
Date Available in IDEALS:2012-10-23
Identifier in Online Catalog:5290866


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