Files in this item



application/pdfECE499-Sp2009-song.pdf (724kB)Restricted to U of Illinois
(no description provided)PDF


Title:Tissue Characterization Using Ultrasonic Backscatter Technique
Author(s):Song, Jun
Contributor(s):O'Brien, William D., Jr.
tissue characterization
ultrasonic backscatter
backscatter modeling
cancer detection
Abstract:Ultrasonic backscatter technique has shown promising capability for noninvasive detection of cancers. Its theoretical framework and measurement techniques have been successfully used to differentiate some tumors. However, the scattering models developed to describe the statistical properties of biological tissues have not been verified. The objective of this study is to evaluate three theoretical scattering models which relate the backscatter coefficient (BSC) to effective scatterer diameter (ESD) and effective acoustic concentration (EAC) of biological tissue. The three scattering models are fluid-filled sphere model (FFSM), spherical Gaussian model (SGM), and concentric sphere model (CSM). Biological phantoms are used as simple models of real tissues, in which cells are suspended in a medium. The estimation of ESD is studied by using two types of cells of different sizes, one being the Chinese hamster ovary (CHO) cell with an average diameter of 10 μm and the other being the 4T1 mouse mammary tumor (4T1) cell with an average diameter of 30 μm. The estimation of EAC is studied by varying number densities of cells in biological phantoms. Estimations are determined by comparing the measured power spectrum with that described by the theoretical models.
Issue Date:2009-05
Publication Status:unpublished
Peer Reviewed:not peer reviewed
Date Available in IDEALS:2014-01-23

This item appears in the following Collection(s)

Item Statistics