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Browse Graduate Dissertations and Theses at Illinois by Contributor "Xiang, Yang"
Now showing items 1-6 of 6
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(2010-05-14)While cystic fibrosis (CF) is commonly thought of as a lung disease, since it’s first description 70 years ago we have come to understand that loss of CFTR (cystic fibrosis transmembrane conductance regulator) function ...
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(2012-02-01)Shp2 (Src Homology 2 Domain-containing Protein Tyrosine Phosphatase 2) is a pivotal player in various signaling pathways in response to growth factors. It contains two SH2 domains (N-SH2 and C-SH2), a phosphatase catalytic ...
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(2012-02-06)Heart disease and diabetes mellitus are growing epidemics, consistently ranking within the top ten causes of death in the United States. Both diseases are associated with cardiac remodeling, including cellular growth and ...
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(2011-05-25)Neutrophils play a critical role in host defense against invading pathogens. Chemotaxis, the directed migration of cells, allows neutrophil to seek out the sites of inflammation and infection. Neutrophil chemotaxis as well ...
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(2011-05-25)β2AR (β2 adrenoceptor) is a prototypical G-protein coupled receptor (GPCR) that plays an important role in cardiovascular and pulmonary physiology through activation of the classic Gs-adenylate cyclase-cyclic adenosine ...
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(2012-02-01)Despite recent advances in our understanding of biochemical regulation of neutrophil chemotaxis, little is known about how mechanical factors control neutrophils’ persistent polarity and rapid motility. Here, by using a ...
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Now showing items 1-6 of 6