Browse Graduate Dissertations and Theses at Illinois by Subject "YcaO"
Now showing items 1-4 of 4
(2017-07-10)Ribosomally synthesized and posttranslationally modified peptides (RiPPs) are a rapidly growing class of natural products. RiPP precursor peptides can undergo extensive enzymatic tailoring to yield structurally and ...
(2021-03-02)YcaO enzymes are best known to catalyze the ATP-dependent peptide backbone activation and subsequent formation of azoline heterocycles. It has been proposed that YcaO enzymes can also install lactamidines and thioamides ...
(2017-12-07)Natural products, generally defined as metabolites of biotic origin, have a long history as medicines and have remained a fruitful source of new drug leads for multiple diseases in the modern age. Arguably the largest asset ...
(2015-01-21)The thiazole/oxazole-modified microcins (TOMMs) are a recently grouped class of ribosomally synthesized and posttranslationally modified peptides. Encoded by many bacteria and archaea, these natural products occupy a large ...