Files in this item
Files | Description | Format |
---|---|---|
application/pdf ![]() ![]() | (no description provided) |
Description
Title: | Nitrogen Metabolites During Exercise in the Horse |
Author(s): | Miller-Graber, Peggy Ann |
Doctoral Committee Chair(s): | Lawrence, Laurie, |
Department / Program: | Animal Science |
Discipline: | Animal Science |
Degree Granting Institution: | University of Illinois at Urbana-Champaign |
Degree: | Ph.D. |
Genre: | Dissertation |
Subject(s): | Agriculture, Animal Culture and Nutrition |
Abstract: | In experiment one, eight Quarter Horse mares were intravenously infused prior to exercise with either sodium acetate (control) or ammonium acetate to determine the effect of elevated ammonia (NH$\sb3$) levels on fatigue development and muscle metabolism. The horses were exercised on an 11% grade treadmill at 4.4 m/s, carrying 27 kg of lead. Time to fatigue was not (P $>$.05) different between groups. Middle gluteal muscle (im) NH$\sb3$ and lactate increased (P $$.05). Treatment did not (P $>$.05) affect plasma or im ala, glu or gln. Urinary orotic acid/creatinine ratio was not (P $>$.05) affected by exercise or treatment and suggests that the urea cycle was not impaired during exercise. These results did not show any metabolic evidence for a role of increased blood NH$\sb3$ in fatigue development at the level of the central nervous system. In a second experiment, six mature Quarter Horse mares were used in a crossover design to assess the effect of dietary protein level on energy and nitrogen metabolism during exercise. After a 2-wk adaptation to either a 9.0% (control) or an 18.5% crude protein (high-protein: HP) diet, each mare performed an exercise test (ET). The ET was performed in the absorptive stage of digestion and consisted of a 15 min exercise period at 4.5 m/s on an 11% grade treadmill. The dietary treatment did not (P $>$.05) affect heart rate or oxygen uptake; however, exercise resulted in an increase (P $$.05) effects due to treatment. A diet by exercise interaction (P $<$.01) occurred for plasma ala, being lower in the HP horses. Plasma urea-N, the urinary urea-N/creatinine and orotic acid/creatinine ratio were higher (P $<$.001) in the HP group. The excretion of urea-N in sweat was also higher (P $<$.001) in the HP group. Substrate utilization during exercise was not altered by excess dietary protein; however, excess protein stimulated nitrogen metabolism in the horse at rest, during submaximal exercise and during recovery. |
Issue Date: | 1988 |
Type: | Text |
Description: | 239 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1988. |
URI: | http://hdl.handle.net/2142/70064 |
Other Identifier(s): | (UMI)AAI8908780 |
Date Available in IDEALS: | 2014-12-15 |
Date Deposited: | 1988 |
This item appears in the following Collection(s)
-
Dissertations and Theses - Animal Sciences
-
Graduate Dissertations and Theses at Illinois
Graduate Theses and Dissertations at Illinois