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Title:Metabolism of Two Model Xenobiotics in Cultured Plant Cells
Author(s):Blair, Louis Curtis
Department / Program:Agronomy
Degree Granting Institution:University of Illinois at Urbana-Champaign
Subject(s):Biology, Plant Physiology
Abstract:Plant cells in culture were found to oxygenate two model xenobiotics. Para-chlorophenyl methyl sulfide was S-oxidized by carrot, cotton, tobacco, alfalfa, and blacknightshade cell cultures. The rates of S-oxygenation by cultured plant cells were comparable to the rates in animal tissue preparations. The plant cell metabolism of the promutagen-procarcinogen 2-aminofluorene was evaluated by a mutagen bioassay. The mutagenic activation of 2-aminofluorene by cultured plant cells was detected by the induction of reverse mutation at the his locus of Salmonella typhumerium. A photoautotrophic cotton cell culture was developed to facilitate xenobiotic metabolism research in photosynthetic cultured plant cells.
Issue Date:1983
Description:98 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1983.
Other Identifier(s):(UMI)AAI8324510
Date Available in IDEALS:2014-12-16
Date Deposited:1983

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