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Title:Design of Heterogeneous Surfaces for Polymer Adsorption
Author(s):Huang, Yu-Wen
Doctoral Committee Chair(s):Vinay K. Gupta
Department / Program:Chemical and Biomolecular Engineering
Discipline:Chemical and Biomolecular Engineering
Degree Granting Institution:University of Illinois at Urbana-Champaign
Subject(s):Engineering, Biomedical
Abstract:The study of adsorption of a globular protein with intrinsic chemical heterogeneity was performed to highlight the role of the nature of adsorbates. On a chemically homogeneous surface, unlike flexible homopolymers, the adsorption kinetics of protein were strongly affected by the chemical properties of surfaces. The adsorption behavior on chemically heterogeneous surfaces was investigated in the case where the heterogeneity was on a molecular scale, nanometer scale, and micron scale. The kinetics indicated that macroscopic interfacial energy as well as the length scale of heterogeneity played a critical role in governing the adsorption characteristics. Morphological measurements by tapping mode AFM revealed that when the dimension of surface heterogeneity was commensurate with the protein, the heterogeneity affected the adsorption characteristics significantly.
Issue Date:2003
Description:156 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2003.
Other Identifier(s):(MiAaPQ)AAI3101868
Date Available in IDEALS:2015-09-25
Date Deposited:2003

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