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Title:Microfluidics for Biomolecular Studies
Author(s):Toepke, Michael W.
Doctoral Committee Chair(s):Kenis, Paul J.A.
Department / Program:Chemical and Biomolecular Engineering
Discipline:Chemical and Biomolecular Engineering
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Engineering, Chemical
Abstract:Large-scale integrated microfluidic networks were designed and fabricated in order to carry out large combinatorial synthesis and screening. The microfluidic devices contained a series of small chambers with a total volume of one nanoliter to contain each of the combinations in the screening library. The library screen was carried out using a label-free sensor that was integrated into the microfluidic device. The sensor identified strongly binding ligands in a combinatorial screen of antibodies.
Issue Date:2006
Type:Text
Language:English
Description:109 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2006.
URI:http://hdl.handle.net/2142/82389
Other Identifier(s):(MiAaPQ)AAI3243012
Date Available in IDEALS:2015-09-25
Date Deposited:2006


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