Files in this item
| Files | Description | Format |
|---|---|---|
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application/pdf  3243012.pdf (4MB) | (no description provided) |
Description
| Title: | Microfluidics for Biomolecular Studies |
| Author(s): | Toepke, Michael W. |
| Doctoral Committee Chair(s): | Kenis, Paul J.A. |
| Department / Program: | Chemical and Biomolecular Engineering |
| Discipline: | Chemical and Biomolecular Engineering |
| Degree Granting Institution: | University of Illinois at Urbana-Champaign |
| Degree: | Ph.D. |
| Genre: | Dissertation |
| Subject(s): | Engineering, Chemical |
| Abstract: | Large-scale integrated microfluidic networks were designed and fabricated in order to carry out large combinatorial synthesis and screening. The microfluidic devices contained a series of small chambers with a total volume of one nanoliter to contain each of the combinations in the screening library. The library screen was carried out using a label-free sensor that was integrated into the microfluidic device. The sensor identified strongly binding ligands in a combinatorial screen of antibodies. |
| Issue Date: | 2006 |
| Type: | Text |
| Language: | English |
| Description: | 109 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2006. |
| URI: | http://hdl.handle.net/2142/82389 |
| Other Identifier(s): | (MiAaPQ)AAI3243012 |
| Date Available in IDEALS: | 2015-09-25 |
| Date Deposited: | 2006 |
This item appears in the following Collection(s)
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Dissertations and Theses - Chemical and Biomolecular Engineering
Dissertations and Theses - Chemical and Biomolecular Engineering -
Graduate Dissertations and Theses at Illinois
Graduate Theses and Dissertations at Illinois