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Description
Title: | Microfluidics for Biomolecular Studies |
Author(s): | Toepke, Michael W. |
Doctoral Committee Chair(s): | Kenis, Paul J.A. |
Department / Program: | Chemical and Biomolecular Engineering |
Discipline: | Chemical and Biomolecular Engineering |
Degree Granting Institution: | University of Illinois at Urbana-Champaign |
Degree: | Ph.D. |
Genre: | Dissertation |
Subject(s): | Engineering, Chemical |
Abstract: | Large-scale integrated microfluidic networks were designed and fabricated in order to carry out large combinatorial synthesis and screening. The microfluidic devices contained a series of small chambers with a total volume of one nanoliter to contain each of the combinations in the screening library. The library screen was carried out using a label-free sensor that was integrated into the microfluidic device. The sensor identified strongly binding ligands in a combinatorial screen of antibodies. |
Issue Date: | 2006 |
Type: | Text |
Language: | English |
Description: | 109 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2006. |
URI: | http://hdl.handle.net/2142/82389 |
Other Identifier(s): | (MiAaPQ)AAI3243012 |
Date Available in IDEALS: | 2015-09-25 |
Date Deposited: | 2006 |
This item appears in the following Collection(s)
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Dissertations and Theses - Chemical and Biomolecular Engineering
Dissertations and Theses - Chemical and Biomolecular Engineering -
Graduate Dissertations and Theses at Illinois
Graduate Theses and Dissertations at Illinois