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Title:Transport-Kinetic Processes and Surface Chemistry in Biosensor Design
Author(s):Vijayendran, Ravi Albert
Doctoral Committee Chair(s):Leckband, Deborah E.
Department / Program:Chemical Engineering
Discipline:Chemical Engineering
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Engineering, Biomedical
Abstract:Finally, sample mixing is examined as a potential method to improve the performance of microfluidic biosensors. We attempt to mix sections of the sample solution where the analyte concentration is high with other sections where it is low, and thereby reduce the sensor response time when the detection kinetics are diffusion-limited. A serpentine micromixer, originally designed to mix two fluids in bulk solution via "chaotic advection," is used to mix the sample as it passes through a surface plasmon resonance biosensor. These experiments indicate that such "solution-based" mixing strategies can be effective in microfluidic biosensors.
Issue Date:2001
Type:Text
Language:English
Description:124 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2001.
URI:http://hdl.handle.net/2142/82485
Other Identifier(s):(MiAaPQ)AAI9996698
Date Available in IDEALS:2015-09-25
Date Deposited:2001


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