Files in this item

FilesDescriptionFormat

application/pdf

application/pdf3337960.pdf (3MB)Restricted to U of Illinois
(no description provided)PDF

Description

Title:Cognitive Effects of Estrogens During Aging
Author(s):Wang, Victor C.
Doctoral Committee Chair(s):Schantz, Susan L.
Department / Program:Neuroscience
Discipline:Neuroscience
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Biology, Neuroscience
Abstract:To investigate possible neurochemical mechanisms, densities of D1 and D2 dopamine receptors and dopamine transporter (DAT) were measured in the prefrontal cortex of genistein-treated rats by Western blot. D1 and D2 densities did not differ between groups. However, DAT density was lower in the control group relative to the genistein groups. DAT was also lower in old rats. These results suggest that different aspects of executive function are differentially sensitive to estrogen or genistein as well as aging, and that altered prefrontal dopamine could play an important role in mediating the effects of estrogens on executive function.
Issue Date:2008
Type:Text
Language:English
Description:185 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2008.
URI:http://hdl.handle.net/2142/82521
Other Identifier(s):(MiAaPQ)AAI3337960
Date Available in IDEALS:2015-09-25
Date Deposited:2008


This item appears in the following Collection(s)

Item Statistics