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Title:The Effects of Lactational and Gestational Exposure to 2,3,7,8-Tetrachlorodibenzo-P-Dioxin or Coplanar PCBs on Spatial Learning and Memory
Author(s):Seo, Byung-Woun
Doctoral Committee Chair(s):Schantz, Susan L.
Department / Program:Neuroscience
Degree Granting Institution:University of Illinois at Urbana-Champaign
Subject(s):Psychology, Psychobiology
Abstract:One way in which rats are able to solve the RAM without employing memory systems is by using a response strategy. The most obvious response strategy that would yield better performance on the RAM is adjacent arm selection. A final study was conducted, in which TCDD-exposed animals were tested on the 8-arm RAM with all of the arms baited or on the 12-arm RAM with only 8 of the 12 arms baited. It was hypothesized that if TCDD-exposed rats had better memory, they should show improvements relative to controls on both tasks. The final study again replicated the reduction in errors on the 8-arm RAM in the TCDD-exposed animals. However, the TCDD-exposed rats did not differ from the controls on the 12-arm RAM. These results suggested that the TCDD-exposed rats were using a response strategy to solve the 8-arm RAM task, but surprisingly there was no indication of increased adjacent arm patterning in these animals. It was concluded that the TCDD-exposed animals probably do not have enhanced spatial memory. (Abstract shortened by UMI.).
Issue Date:1999
Description:139 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1999.
Other Identifier(s):(MiAaPQ)AAI9944994
Date Available in IDEALS:2015-09-25
Date Deposited:1999

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