Structural and Functional Models of the Iron -Only Hydrogenase Enzymes

Lawrence, Joshua D.

Use this link to cite this item:

Files in this item

Files	Description	Format
application/pdf 3070020.pdf (7MB)	(no description provided)	PDF

Title:	Structural and Functional Models of the Iron -Only Hydrogenase Enzymes
Author(s):	Lawrence, Joshua D.
Doctoral Committee Chair(s):	Rauchfuss, Thomas B.
Department / Program:	Chemistry
Discipline:	Chemistry
Degree Granting Institution:	University of Illinois at Urbana-Champaign
Degree:	Ph.D.
Genre:	Dissertation
Subject(s):	Chemistry, Biochemistry
Abstract:	New structural models for the H2-oxidizing state of the H-cluster were synthesized. Electron-rich polyisocyano compounds Fe2(S 2CnH2n)(CO)2(CNMe)4 undergo oxidatively induced reaction with additional CNMe to give [Fe2(S2CnH 2n)(CNMe)7](PF6)2, the first members of a new class of iron thiolates. Crystallographic characterization established that the 34 e- dinuclear core resembles the [Fe 2]H portion of the H-cluster. Treatment of [Fe2(S 2C3H6)(CNMe)7](PF6) 2 with excess CNMe led to [Fe2(S2C3H 6)(CNMe)10](PF6)2; the rate of addition of isocyanide is increased by more than three orders of magnitude under photolytic conditions.
Issue Date:	2002
Type:	Text
Language:	English
Description:	161 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2002.
URI:	http://hdl.handle.net/2142/84070
Other Identifier(s):	(MiAaPQ)AAI3070020
Date Available in IDEALS:	2015-09-25
Date Deposited:	2002