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Title:Electronic Relaxation Properties of Gadolinium Based MRI Contrast Agents
Author(s):Kang, Hoon
Doctoral Committee Chair(s):Belford, R. Linn; Clarkson, Robert B.
Department / Program:Chemistry
Discipline:Chemistry
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Health Sciences, Radiology
Abstract:In order to increase our understanding of the relationship between the gadolinium chelate's chemical structure and its effectiveness as a MRI contrast agent, we have prepared and studied a number of chelates with ranging characteristics. We have found that the metal-ligand binding of chelates is important in determining the ZFS and tauv. We also investigated the role of the cage rigidity of the chelate, and studied its effect on tauv. Finally, we hope that our study can stimulate synthesis 'Smart Contrast Agents' that utilizes the changes in electron relaxation rate upon changes in structure.
Issue Date:2002
Type:Text
Language:English
Description:142 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2002.
URI:http://hdl.handle.net/2142/84081
Other Identifier(s):(MiAaPQ)AAI3070345
Date Available in IDEALS:2015-09-25
Date Deposited:2002


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