Part I. Isoindolin-1-One Receptors for CG Base Pairs in a DNA Triple Helix. Part II. Cross-Linked Dendrimer Hosts Containing Reporter Groups for Amine Guests

Mertz, Paul Eric

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Title:	Part I. Isoindolin-1-One Receptors for CG Base Pairs in a DNA Triple Helix. Part II. Cross-Linked Dendrimer Hosts Containing Reporter Groups for Amine Guests
Author(s):	Mertz, Paul Eric
Doctoral Committee Chair(s):	Zimmerman, Steven C.
Department / Program:	Chemistry
Discipline:	Chemistry
Degree Granting Institution:	University of Illinois at Urbana-Champaign
Degree:	Ph.D.
Genre:	Dissertation
Subject(s):	Chemistry, Biochemistry
Abstract:	RCM of the dendrimer followed by hydrolysis created a cross-linked host, which was used in UV/Vis titrations. These studies showed that the dendritic hosts binds unbranched diamines 53 to 85-fold more tightly than it binds monoamines. Furthermore, an assay of the dendrimer with several amine and alcohol guests indicated that it has high selectivity for guests most similar to its original template. However, control studies indicated that this selectivity is due to differing reactivities of guests. Dendrimers containing the core reporter group are a significant expansion in the scope of dendrimer-based monomolecular imprinting.
Issue Date:	2003
Type:	Text
Language:	English
Description:	175 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2003.
URI:	http://hdl.handle.net/2142/84103
Other Identifier(s):	(MiAaPQ)AAI3086139
Date Available in IDEALS:	2015-09-25
Date Deposited:	2003