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Description
Title: | I. Chemoselective Dehydrative Glycosylation With Application Toward Oligosaccharide Synthesis. II. Sulfide-Mediated Direct Glycosylation of C(1)-Hydroxyl Glycosyl Donors. III. Studies Toward the Total Synthesis of Auriside A |
Author(s): | Nguyen, Hien Minh |
Doctoral Committee Chair(s): | Gin, David Y. |
Department / Program: | Chemistry |
Discipline: | Chemistry |
Degree Granting Institution: | University of Illinois at Urbana-Champaign |
Degree: | Ph.D. |
Genre: | Dissertation |
Subject(s): | Chemistry, Organic |
Abstract: | Our efforts for the development of novel strategies for the total synthesis of auriside A are present in the third part of the dissertation. The hemiacetal disaccharide portion of auriside A is successfully synthesized. The convergent synthesis of the auriside aglycon component is accomplished in 17 linear steps using the Mukaiyama aldol reaction, the intramolecular Mitsunobu macrolactonization, and the Julia olefination for the installation of the C(5)-stereogenic center, the 14-membered macrolactone, and the conjugated bromodiene moiety, respectively. |
Issue Date: | 2003 |
Type: | Text |
Language: | English |
Description: | 301 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2003. |
URI: | http://hdl.handle.net/2142/84128 |
Other Identifier(s): | (MiAaPQ)AAI3111623 |
Date Available in IDEALS: | 2015-09-25 |
Date Deposited: | 2003 |
This item appears in the following Collection(s)
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Dissertations and Theses - Chemistry
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Graduate Dissertations and Theses at Illinois
Graduate Theses and Dissertations at Illinois