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Title:I. Chemoselective Dehydrative Glycosylation With Application Toward Oligosaccharide Synthesis. II. Sulfide-Mediated Direct Glycosylation of C(1)-Hydroxyl Glycosyl Donors. III. Studies Toward the Total Synthesis of Auriside A
Author(s):Nguyen, Hien Minh
Doctoral Committee Chair(s):Gin, David Y.
Department / Program:Chemistry
Discipline:Chemistry
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Chemistry, Organic
Abstract:Our efforts for the development of novel strategies for the total synthesis of auriside A are present in the third part of the dissertation. The hemiacetal disaccharide portion of auriside A is successfully synthesized. The convergent synthesis of the auriside aglycon component is accomplished in 17 linear steps using the Mukaiyama aldol reaction, the intramolecular Mitsunobu macrolactonization, and the Julia olefination for the installation of the C(5)-stereogenic center, the 14-membered macrolactone, and the conjugated bromodiene moiety, respectively.
Issue Date:2003
Type:Text
Language:English
Description:301 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2003.
URI:http://hdl.handle.net/2142/84128
Other Identifier(s):(MiAaPQ)AAI3111623
Date Available in IDEALS:2015-09-25
Date Deposited:2003


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