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Description
Title: | From Prohormones to Neuropeptides: Mass Spectrometric and Bioinformatic Approaches |
Author(s): | Hummon, Amanda B. |
Doctoral Committee Chair(s): | Sweedler, Jonathan V. |
Department / Program: | Chemistry |
Discipline: | Chemistry |
Degree Granting Institution: | University of Illinois at Urbana-Champaign |
Degree: | Ph.D. |
Genre: | Dissertation |
Subject(s): | Chemistry, Analytical |
Abstract: | To test the predictive models on a larger dataset, another organism was studied. The genome of the western honey bee, Apis mellifera, is being sequenced. After deducing the neuropeptide genes through bioinformatic and mass spectrometric approaches, the neuropeptides are predicted with the Aplysia-based algorithms. To verify all predictions, the peptide sequences are confirmed by electrospray quadrupole mass spectrometry (ESI-Q) TOF-MS. Employing information from additional species will help to test our current prediction schemes and develop more accurate algorithms. |
Issue Date: | 2004 |
Type: | Text |
Language: | English |
Description: | 212 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2004. |
URI: | http://hdl.handle.net/2142/84152 |
Other Identifier(s): | (MiAaPQ)AAI3153322 |
Date Available in IDEALS: | 2015-09-25 |
Date Deposited: | 2004 |
This item appears in the following Collection(s)
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Dissertations and Theses - Chemistry
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Graduate Dissertations and Theses at Illinois
Graduate Theses and Dissertations at Illinois