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Title:Probing Biological Systems at the Single Molecule Level: Studies of the Homophilic Binding of the Neural Cell Adhesion Molecule (Ncam) and Phase Dependent Lipid Anchorage Strength
Author(s):Wieland, Julie A.
Doctoral Committee Chair(s):Gewirth, Andrew A.; Leckband, Deborah E.
Department / Program:Chemistry
Discipline:Chemistry
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Chemistry, Analytical
Abstract:Force probe measurements were also used to study environmental effects on the intermolecular strength of lipids within a membrane. In this case the anchorage strength of lipids in fluid versus gel lipid layers was probed to determine how temperature affects the adhesion properties between adjacent lipid molecules. From this study we have shown that it takes almost three times the force to extract a lipid from a gel phase lipid layer as opposed a fluid phase layer.
Issue Date:2005
Type:Text
Language:English
Description:254 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2005.
URI:http://hdl.handle.net/2142/84204
Other Identifier(s):(MiAaPQ)AAI3199173
Date Available in IDEALS:2015-09-25
Date Deposited:2005


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