Modified Farnesyl Diphosphate, Germacrane, and Eremophilane Sesquiterpenes as Probes for Capsidiol *Biosynthesis

Zhao, Yuxin
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Title:Modified Farnesyl Diphosphate, Germacrane, and Eremophilane Sesquiterpenes as Probes for Capsidiol *Biosynthesis
Author(s):Zhao, Yuxin
Doctoral Committee Chair(s):Coates, Robert M.
Department / Program:Chemistry
Discipline:Chemistry
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Chemistry, Organic
Abstract:The final part of this thesis discusses the preparation and characterization of two deoxycapsidiols as well as a series of capsidiol analogs including epiaristolochene and two isomers. Overall, ten capsidiol derivatives were synthesized from capsidiol and sent to collaborators for various biological evaluations. In addition, this library was evaluated for antifungal activity in order to establish preliminary structure-activity relationships.
Issue Date:2005
Type:Text
Language:English
Description:186 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2005.
URI:http://hdl.handle.net/2142/84208
Other Identifier(s):(MiAaPQ)AAI3199199
Date Available in IDEALS:2015-09-25
Date Deposited:2005


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