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Title:Interrogation of Yeast Responses to Anaerobic Growth Conditions at the Intact Protein Level Using Improved Top-Down Proteomics
Author(s):Du, Yi
Doctoral Committee Chair(s):Kelleher, Neil L.
Department / Program:Chemistry
Discipline:Chemistry
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Chemistry, Analytical
Abstract:Taking advantage of further development of the front-end platform and metabolic labeling quantitative strategy, top-down proteomics was employed to investigate the response of Saccharomyces cerevisiae towards anaerobiosis. Approximately 150 protein pairs were measured with 4 differential expressions determined including an aerobic and anaerobic isoform. Direct comparison of PTM patterns between two cell states was also accomplished through top-down proteomics.
Issue Date:2005
Type:Text
Language:English
Description:114 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2005.
URI:http://hdl.handle.net/2142/84209
Other Identifier(s):(MiAaPQ)AAI3202086
Date Available in IDEALS:2015-09-25
Date Deposited:2005


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